Process for attenuated varicella zoster virus vaccine...

Details Process for attenuated varicella zoster virus vaccine... Process for attenuated varicella zoster virus vaccine...

C - Chemistry, Metallurgy

12

N

C12N 7/00 (2006.01) A61K 39/25 (2006.01) C12N 5/02 (2006.01) C12N 7/04 (2006.01)

Patent

CA 2097019

A live, attenuated varicella zoster virus vaccine is produced with enhanced yield of VZV. The new process makes mass production of a live VZV vaccine more practical. In addition, optimized monolayer cell culture conditions provide a process for maximizing monolayer cell density which is useful for enhancing viral vaccine production. According to this process, cell densities approaching 500,000 cells/cm2 are routinely achieved in conventional culture vessels.

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