Process for .beta.-hydroxy-.alpha.-amino acids

Details Process for .beta.-hydroxy-.alpha.-amino acids Process for .beta.-hydroxy-.alpha.-amino acids

C - Chemistry, Metallurgy

12

P

C12P 13/04 (2006.01) C07C 229/24 (2006.01) C12N 9/10 (2006.01) C12P 13/08 (2006.01)

Patent

CA 2043761

Abstract .beta.-Hydroxy-.alpha.-amino acids are obtained via serine hydroxymethyltransferase catalyzed condensation of aldehydes with glycine. The predominant product with most aldehydes is the L-erythro diastereomer. For example, succinic semialdehyde methyl ester is condensed with glycine in the process to provide L-erythro .alpha.-amino-.beta.-hydroxy adipic acid mono methyl ester.

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