Process for biological production of amides

Details Process for biological production of amides Process for biological production of amides

C - Chemistry, Metallurgy

12

P

195/86

C12P 13/02 (2006.01) C12N 9/78 (2006.01) C12P 1/04 (2006.01)

Patent

CA 1298222

ABSTRACT In a process for biological production of an amide wherein a nitrile is hydrated into a corresponding amide by the action of a nitrile hydratase originated in a microorganism, the improvement which comprises the use of nitrile hydratase which is obtained by culturing a microorganism of the species Rhodococcus rhodochrous in the presence of a cobalt ion. Aromatic nitriles such as a cyanopyridine as well as aliphatic nitrile such as acrylonitrile are hydrated into the corresponding amides.

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