C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/73 (2006.01) C07D 215/38 (2006.01) C07D 215/40 (2006.01) C07D 215/42 (2006.01) C07D 219/08 (2006.01)
Patent
CA 2269547
A process of converting a hydroxy heteroaromatic compound to an arylamine, comprising the steps of : 1) treating a salt of a hydroxy heteroaromatic compound with an alkylating agent; and 2) treating the reaction mixture with a Smiles solvent system and raising the temperature of the reaction mixture; and a compound made according to the above process.
L'invention porte sur un procédé de conversion d'un composé hétéroaromatique hydroxy en un arylamine. Ce procédé consiste à: (1) traiter un sel d'un composé hétéroaromatique hydroxy avec un agent d'alkylation; et (2) traiter le mélange de réaction avec un système de solvant Smiles et faire monter la température du mélange de réaction. L'invention porte également sur un composé obtenu selon le procédé précité.
Peet Norton P.
Weidner John J.
Aventis Pharmaceuticals Inc.
Hoechst Marion Roussel Inc.
Osler Hoskin & Harcourt Llp
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