Process for cross coupling indoles

Details Process for cross coupling indoles Process for cross coupling indoles

C - Chemistry, Metallurgy

07

D

C07D 209/30 (2006.01)

Patent

CA 2552980

The present invention provides a process for making a compound of general formula (I) wherein: R = H or C1-8 alkyl X = C3 -C8 cycloalkyl, C3 -C8 aryl or C3 -C8 alkyl; Y = heteroaryl or aryl; Z = H, HO2C-, C1-8 alkyl O2C-, C1-6 alkyl HNC(O)- and as described herein.

L'invention concerne un procédé de fabrication d'un composé de formule générale (I), dans laquelle R = H ou alkyle C¿1-8? ; X = cycloalkyle C¿3-?C¿8?, aryle C¿3-?C¿8? ou alkyle C¿3-?C¿8 ?; Y = hétéroaryle ou aryle ; Z = H, HO¿2?C-, C¿1-8 ?alkyl O¿2?C-, C¿1-6? alkyl HNC(O)- ; et tel que défini dans la description.

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