Process for cultivating animal cells comprising the feeding...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/02 (2006.01)

Patent

CA 2610315

A process for cultivating animal cells producing complex proteins, wherein one plant-derived peptone or a combination of plant-derived peptones is fed to the cell culture, as well as a method for reducing the toxic effect of over- feeding amino acids during a fed-batch process for cultivating animal cells producing complex proteins.

L'invention concerne un procédé permettant de cultiver des cellules animales produisant des protéines complexes. Selon ce procédé un peptone dérivé d'une plante ou une combinaison de peptones dérivés de plante est amené à une culture cellulaire. L'invention concerne également un procédé permettant de diminuer l'effet toxique d'une suralimentation en acides aminés durant un processus de fermentation semi-continu pour cultiver des cellules animales produisant des protéines complexes.

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