C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/118.5
C07D 499/04 (2006.01) C07D 499/00 (2006.01)
Patent
CA 1210388
PROCESS FOR DEBROMINATION OF DIBROMO- PENICILLANIC ACID AND DERIVATIVES Abstract A process for the debromination of 6-monobromo- and 6,6-dibromopenicillanic acid, and various derivatives thereof, by the action of a bisulfite salt. The debrominated compounds produced find various utilities, as beta-lactamase inhibitors useful in therapy in combination with known beta-lactam antibiotics, or as intermediates in the further synthesis of useful beta- lactam compounds.
455814
Pirie Donald K.
Weeks Paul D.
Limited Pfizer
Smart & Biggar
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