Process for detecting modulation of nad(p)h oxidoreductase

Details Process for detecting modulation of nad(p)h oxidoreductase Process for detecting modulation of nad(p)h oxidoreductase

C - Chemistry, Metallurgy

12

Q

C12Q 1/26 (2006.01) C12Q 1/32 (2006.01)

Patent

CA 2398789

A process is described for detecting modulation of NAD(P)H and/or a NAD(P)H dependent oxidoreductase ("NDO") in or by a biological system which comprises NAD(P)H and an NDO. The process comprises generating a detectable marker of NAD(P)H modulation, and detecting said detectable marker. The oxidoreductase may be cytochrome p450 BM3 from Bacillus megaterium in E.coli.

L'invention concerne un procédé de détection de la modulation de NAD(P)H et/ou d'une oxydoréductase dépendante de NAD(P)H (NDO) dans ou par un système biologique comportant NAD(P)H et un NDO. Ce procédé comporte la production d'un marqueur détectable de la modulation de NAD(P)H et la détection dudit marqueur détectable.

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