Process for detecting proteins specific to hypertension in...

G - Physics – 01 – N

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150/9, 204/99.02

G01N 27/26 (2006.01) G01N 27/447 (2006.01) G01N 33/68 (2006.01)

Patent

CA 1155738

ABSTRACT OF THE DISCLOSURE A process for diagnosing the presence of hyperten- sion or a predisposition to hypertension in a mammal com- prises detecting the presence in a body fluid of the mammal of at least one protein associated with hyperten- sion wherein the protein has a relative molecular weight of about 10,000 daltons to about 17,000 daltons. In humans, the process detects the presence of or predisposi- tion to essential hypertension as distinguished from secondary hypertension. A preferred analytical method is discontinuous sodium dodecyl sulfate polyacrylamide gel electrophoresis.

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