Process for esterification of .alpha.-l-aspartyl-l-...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/02 (2006.01) C07K 5/072 (2006.01)

Patent

CA 1161381

Case 2148/2 PROCESS FOR ESTERIFICATION OF .alpha.-L-ASPARTYL-L-PHENYLALANINE Abstract of the Disclosure A process for selectively esterifying .alpha.-L-aspartyl- L-phenylalanine to the corresponding alkyl esters using a proteolytic enzyme with specific esterase activity is described. The process is carried out in an aqueous-alcohol medium in which the alcohol concentration is sufficient to reverse the esterase activity. The .alpha.-L-aspartyl-L- phenylalanine alkyl esters so produced are useful as artificial sweeteners.

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