Process for evaluating the sensitizing and/or irritant...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/02 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2226426

The invention concerns a process for evaluating the sensitizing and/or irritant and/or allergenic potential of a product, using a simultaneous culture of keratinocytes and precursor Langerhans' cells. The invention also concerns a process for evaluating a product capable of moderating or even inhibiting the sensitizing and/or irritant and/or allergenic effect of another product.

L'invention concerne un procédé d'évaluation du potentiel sensibilisant et/ou irritant et/ou allergène d'un produit, mettant en oeuvre une culture simultanée de kératinocytes et de précurseurs de cellules de Langerhans. L'invention concerne également un procédé pour évaluer un produit capable de moduler voire inhiber l'effet sensibilisant et/ou irritant et/ou allergène d'un autre produit.

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