C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/475 (2006.01) A23K 1/16 (2006.01) A61K 38/18 (2006.01) C07K 1/30 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2248843
The invention relates to a process for extraction of a growth factor complex and is characterised in that water is added to natural and growth-factor containing material, the pH value is set by the addition of acid at 2.5 to 3.2, and the resultant product is separated off. The growth factor complex is produced from the mother liquor by adding an organic solvent which can be mixed with water, is separated off from the liquid phase and dried, and the resultant powder is optionally dialysed.
Cette invention concerne un procédé qui permet d'obtenir un complexe de facteurs de croissance (Growth Factor Complex) et qui est caractérisé par le fait que l'on mélange la matière naturelle contenant des facteurs de croissance avec de l'eau, on règle le pH entre 2,5 et 3,2 par addition d'acide, on sépare le produit ainsi obtenu et on précipite le Growth Factor Complex contenu dans la solution mère par adjonction d'un solvant organique miscible dans l'eau, on le sépare de la phase liquide, on le sèche et on effectue éventuellement une dialyse de la poudre obtenue.
Hofmann Dieter
Meyer Hans
Wasmer Hermann
Bioequal Ag
Gowling Lafleur Henderson Llp
Ipr-Institute For Pharmaceutical Research Ag
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