C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 477/20 (2006.01) A61J 3/00 (2006.01) A61K 9/19 (2006.01) A61K 31/40 (2006.01) A61K 31/407 (2006.01) A61K 47/04 (2006.01) A61P 31/04 (2006.01) C07D 477/00 (2006.01)
Patent
CA 2426680
The present invention involves a process for preparing a stable final formulation product of a compound of formula (I) or its pharmaceutically acceptable salt, hydrate or solvate by incorporating a suitable carbon dioxide source to an unstable monosodium adduct of carbapenem antibiotic compound.
L'invention concerne un procédé pour l'élaboration d'une formulation finale stable de composé représenté par la formule (I), y compris un sel, hydrate, ou solvate pharmaceutiquement acceptable, par incorporation d'une source de dioxyde de carbone appropriée à un adduit monosodium instable de composé antibiotique carbapenem.
Al-Dehneh Anthony
Hunke William A.
Illig Kathleen J.
Kanike Anand
Patel Hiren
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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