Process for heterogeneous nucleophilic substitution...

C - Chemistry – Metallurgy – 07 – C

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C07C 69/157 (2006.01) C07C 17/20 (2006.01) C07C 29/58 (2006.01) C07C 41/01 (2006.01) C07C 69/14 (2006.01) C07C 67/00 (2006.01)

Patent

CA 1133932

ABSTRACT OF THE DISCLOSURE The invention relates to a process for nucleophilic substitution reactions. According to the invention the reaction is carried out in a heterogeneous system, consisting of a solid and a dissolved reactant, one or several organic and/or amino compounds and water. The volume of the water is at the most 100 % of the volume of the organic solvent and preferably 5 %. According to the invention the anhydrous reaction medium which is difficult to ensure, is not necessary and the use of the expensive and industrial scales un- available crown ethers is eliminated.

313793

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