C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) B01J 19/00 (2006.01) C07H 21/00 (2006.01) C07K 1/04 (2006.01) C07K 17/00 (2006.01)
Patent
CA 2490675
Protective groups which may be cleaved with an activatable deprotecting reagents are employed to achieve a highly sensitive, high resolution, combinatorial synthesis of pattern arrays of diverse polymers. In preferred embodiments of the instant invention, the activatable deprotecting reagent is a photoacid generator and the protective groups are DMT for nucleic acids and tBOC for amino acids. This invention has a wide variety of applications and is particularly useful for the solid phase combinatorial synthesis of polymers.
Goldberg Martin J.
Kuimelis Robert G.
Mcgall Glenn H.
Parker Nineveh A.
Xu Guangyu
Affymetrix Inc.
Smart & Biggar
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