Process for hydroformylation of an olefin

C - Chemistry – Metallurgy – 07 – C

Patent

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260/573.2

C07C 45/50 (2006.01) C07C 47/02 (2006.01)

Patent

CA 2027991

A process for hydroformylation of an olefin, which comprises reacting an olefin with carbon monoxide and hydrogen in the presence of a rhodium catalyst having a trivalent organic phosphorus compound as a ligand, wherein the hydroformylation reaction is conducted by two stage reactor systems i.e. a first stage reactor system comprising a reactor or reactors having a mixing characteristic of the liquid phase being substantially of complete mixing type, and a second stage reactor system being a reaction system of a catalyst solution circulating type and comprising a reactor or reactors having a mixing characteristic of piston flow type wherein when the mixing characteristic of the liquid phase is represented by a diffusion model, a non-dimensional number U (hereinafter referred to as a "flow mixing parameter") defined by the formula (I): U = ~L/2~ (I) wherein ~ is an average flow velocity (cm/sec), L is the length (cm) of the reaction layer, and ~ is an average diffusion coefficient (cm2/sec), is at least 0.4, a gaseous product or gas-liquid mixture discharged from the first stage reactor system, is separated into a stream containing the unreacted olefin and other stream, and a part or whole of the stream containing the unreacted olefin is supplied to the second stage reactor system.

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