Process for improving flow and compression of tableting...

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A23G 3/00 (2006.01) A61K 9/20 (2006.01) A61K 31/192 (2006.01) A61K 31/59 (2006.01) A61K 47/10 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2301282

A method of forming a flowable tablet blend having cohesive properties comprising, mixing a shearform matrix and a binder, densifying said mixture to uniformly localize said binder into said uncured shearform matrix and form a compacted mass, and sizing said compacted mass to form flowable particles of a blend. Tablets made from such blends are disclosed herein.

L'invention concerne un procédé pour former un mélange coulant pour comprimés, présentant des propriétés cohésives. Ce procédé consiste à mélanger une matrice amorphe et un liant, à densifier ce mélange pour répartir uniformément ledit liant dans ladite matrice amorphe crue et former une masse compactée, et à calibrer ladite masse compactée pour former des particules coulantes d'un mélange. L'invention concerne également des comprimés fabriqués à partir de ces mélanges.

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