Process for l-dopa

Details Process for l-dopa Process for l-dopa

C - Chemistry, Metallurgy

07

C

260/516.3

C07C 227/12 (2006.01) C07C 227/24 (2006.01) C07C 229/34 (2006.01) C07C 229/36 (2006.01)

Patent

CA 1292478

2189S/1040A 17268 . TITLE OF THE INVENTION PROCESS FOR L-DOPA ABSTRACT OF THE DISCLOSURE A process for the preparation of (S)- or L-3-(3,4-dihydroxyphenyl)alanine (L-dopa) is described. The process utilizes water as reaction process solvent and proceeds via formation of an intermediate which can be kinetically resolved in a polar solvent to a precursor of the desired isomer and in which the undesired isomer can be efficiently racemized for reuse.

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