Process for large scale chromatography

Details Process for large scale chromatography Process for large scale chromatography

B - Operations, Transporting

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B01J 39/00 (2006.01) B01D 15/08 (2006.01) B01J 39/26 (2006.01) G01N 30/56 (2006.01) G01N 30/96 (2006.01) G01N 30/32 (2006.01)

Patent

CA 1058337

ABSTRACT OF THE DISCLOSURE Process for chromatographic separation using ion- exchange resin in columns having a diameter in excess of about 1 meter and a height of 2.5 to 6 meters by establis- hing a stabile chromatographic column having a permeability coefficient within a desired range, introducing liquid evenly by gravity across the top of the column and achieving uniform flow of the liquid throughout the length and breadth of the column, utilizing approximately a critical velocity.

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