Process for lysing liposome membrane

Details Process for lysing liposome membrane Process for lysing liposome membrane

G - Physics

01

N

G01N 33/536 (2006.01) A61K 9/127 (2006.01) B01D 17/05 (2006.01) C12Q 1/68 (2006.01) G01N 33/58 (2006.01)

Patent

CA 2074151

ABSTRACT OF THE DISCLOSURE Membranes of liposomes fixing biotin on membrane surfaces thereof can be lysed by a mixed agent comprising a surfactant and avidin. This mechanism can be applied to immunoassay for determining an analyte, e.g. antigen or antibody, wherein liposomes encapsulat- ing a marker and fixing biotin on membrane surfaces thereof are lysed depending on hindrance of an avidin- biotin binding reaction by a specific reaction caused by the analyte.

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