Process for making a stable pharmaceutical preparation of...

A - Human Necessities – 61 – K

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A61K 31/557 (2006.01) A61K 9/48 (2006.01) A61K 9/66 (2006.01)

Patent

CA 1256029

-7- PROCESS FOR MAKING A STABLE PHARMACEUTICAL PREPARATION OF PROSTAGLANDIN E COMPOUNDS, AND/OR 15R FORMS THEREOF Abstract of the Disclosure A process for making a stable pharmaceutical preparation of prostaglandin E compounds and/or 15R forms thereof is disclosed. Prostaglandin E compounds and 15R forms thereof are known to have useful pharmacological actions even if they are used in a vary small amounts. However, they are extremely unstable and, therefore, considerably difficult in application for routine clinical purposes. In order to remove this difficulty, prostaglandin E compounds and 15R forms thereof are formulated into a stable preparation by filling a hard capsule with a solution or a suspension thereof.

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