A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01) A61K 9/26 (2006.01) A61K 9/50 (2006.01) A61K 31/4402 (2006.01) A61K 31/485 (2006.01)
Patent
CA 2383405
The present invention is directed to application of novel process conditions for aqueous coating techniques of water soluble active agents, and its application to production of sustained release beadlets of said agents. The improvement lies in the determination and use of the glass transition point for the water swellable polymer used to produce the sustained release effect, and control of the moisture content of the air by dew point.
L'invention concerne un procédé de revêtement aqueux pour agents à principe actif hydrosolubles, permettant d'élaborer des granules à libération prolongée de ces agents. L'amélioration décrite consiste à déterminer et à utiliser le point de transition vitreuse pour le polymère gonflant dans l'eau qui donne l'effet de libération prolongée, puis à contrôler la teneur en humidité de l'air au point de rosée.
Achanta Anand
Adusumilli Prasad
Deshpande Ganesh
Lech Stanley J.
Oths Phil
Borden Ladner Gervais Llp
Smithkline Beecham Corporation
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