Process for making cholesterol lowering saponins

Details Process for making cholesterol lowering saponins Process for making cholesterol lowering saponins

C - Chemistry, Metallurgy

07

J

C07J 71/00 (2006.01) C07H 13/06 (2006.01) C07J 17/00 (2006.01) C07J 63/00 (2006.01) C07J 75/00 (2006.01)

Patent

CA 2079543

PROCESS FOR MAKING CHOLESTEROL LOWERING SAPONINS ABSTRACT Disclosed is a process for preparing novel compounds containing 5-C-hydroxymethylhexose and a sterol or triterpene. These materi- als, when consumed by humans and animals, lower the cholesterol level in the blood. The compositions are prepared by preparing and then reacting a fluoro or bromo hexaacylated 5-C-hydroxymethylhexose with a sterol. In a second method the hexaacylated 5-C- hydroxymethylhexose is reacted with a sterol in the presence of trimethylsilyl trifluoromethane sulfonate.

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