Process for making hiv protease inhibitors

C - Chemistry – Metallurgy – 07 – D

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C07D 263/52 (2006.01) C07D 241/04 (2006.01) C07D 303/36 (2006.01) C07D 401/06 (2006.01) C07D 405/00 (2006.01) C07D 405/06 (2006.01) C07D 413/06 (2006.01) C07D 413/14 (2006.01) C07D 453/02 (2006.01) C07D 471/04 (2006.01) C07F 9/653 (2006.01)

Patent

CA 2167408

Intermediates of structural formula (A) can be made by reacting a primary or secondary amine with glycosidol or an activated derivative thereof. The process and intermediates are useful for synthesizing HIV protease inhibitor compounds.

On peut préparer des intermédiaires représentés par la formule (A) par réaction d'une amine primaire ou secondaire avec du glycosidol ou un de ses dérivés activés. Le procédé et les intermédiaires sont efficaces pour synthétiser des composés inhibiteurs de la protéase de VIH.

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