C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/233 (2006.01)
Patent
CA 2756031
The invention provides a process for the preparation of a compound of Formula 1; comprising coupling a carboxylic acid of Formula 2; with an aniline of Formula 3; in the presence of a coupling agent.
La présente invention concerne un procédé pour la préparation d'un composé de Formule 1, comprenant le couplage d'un acide carboxylique de Formule 2 avec une aniline de Formule 3 en présence d'un agent de couplage.
Botfield Martyn C.
Demattei John
Grootenhuis Peter D.j.
Krueger Brian R.
Looker Adam R.
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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