Process for making shaped articles of a thermoplastic resin...

C - Chemistry – Metallurgy – 08 – J

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C08J 9/26 (2006.01) A61L 27/56 (2006.01) C08J 9/00 (2006.01)

Patent

CA 2044397

ABSTRACT OF THE DISCLOSURE A process for producing an article of a synthetic resin material or a thermoplastic resin blend having a microcellular structure comprises dispersing in a solid thermoplastic resin matrix having hydrophilic functional groups a finely divided water-soluble material, shaping the resin matrix containing the water-soluble material into the desired article, and immersing the shaped article in water at suitable temperature to cause the resin matrix to well to an extent of at least about 50% by volume while wet. The immersion causes water to diffuse into the resin matrix and solvate the water-soluble material, which becomes encased in water-filled cells that have solid walls, are substantially closed, and do not form an interconnecting porous network. Articles made by this process include, among others, vascular grafts and organoids. AD-5890

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