C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/555.7, 260/5
C07C 61/06 (2006.01) C07C 103/183 (1980.01)
Patent
CA 1117977
Process for manufacturing D camphorate of L carnitinamide and D camphorate of D carnitinamide ABSTRACT OF THE DISCLOSURE: A process for manufacturing the D camphorate of L carnitinamide and the D camphorate of D carnitinamide is disclosed, wherein D,L carnitinamide hydrochloride is converted to D,L carnitinamide free base which directly reacts with D camphoric acid either as an aqueous suspension or in solid form, thus obtaining a solution of D camphorate of D,L carnitin- amide. The resolution of the optical isomers is achieved by drying this solution and taking up the residue with isopropanol, whereupon the D camphorate of L carnitinamide crystallizes out of the isopropanol solution and the D camphorate of n carnitin- amide remains in solution.
331403
de Witt Paolo
Diamanti Enrico
Cavazza Claudio
Robic Robic & Associes/associates
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