A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/107 (2006.01) A61K 31/415 (2006.01) A61K 38/13 (2006.01) A61K 47/10 (2006.01) A61K 47/44 (2006.01)
Patent
CA 2672973
The present invention relates to new processes for the preparation of oil-in-water emulsions useful in ophthalmic applications. In particular, processes are provided that include preparing a pre-concentrate of the oil-in-water emulsion, and diluting the pre-concentrate obtained to form the desired oil-in-water emulsion. The present invention also provides pharmaceutical compositions comprising an oil-in-water emulsion prepared by an inventive process, and methods of using these compositions for the treatment of an eye disease or condition.
La présente invention porte sur de nouveaux procédés pour la préparation d'émulsions huile-dans-eau utiles dans des applications ophtalmiques. En particulier, l'invention concerne des procédés comprenant la préparation d'un pré-concentré de l'émulsion huile-dans-eau, et la dilution du préconcentré obtenu pour former l'émulsion huile-dans-eau désirée. La présente invention concerne également des compositions pharmaceutiques comprenant une émulsion huile-dans-eau préparée par un procédé de l'invention, et des procédés d'utilisation de ces compositions pour le traitement d'une maladie ou d'un état de l'AEil.
Candillon Pascal
Lafosse Julien
Lallemand Frederic
Lambert Gregory
Rabinovich-Guilatt Laura
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Novagali Pharma Sa
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