Process for micronizing slightly-soluble drug

Details Process for micronizing slightly-soluble drug Process for micronizing slightly-soluble drug

A - Human Necessities

61

K

167/168

A61K 9/14 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2022465

The present invention is directed to a process for micronizing a slightly-soluble drug characterized by subjecting a mixture of said drug and a sugar or sugar alcohol to high-speed stirring comminution or impact comminution. Also provided is a pharmaceutical formulation which comprises the micronized drug.

Procédé de micronisation d'un médicament légèrement soluble caractérisé par la fragmentation par brassage à haute vitesse ou par impact d'un mélange du médicament en question et d'un sucre ou d'un itol. Une formulation pharmaceutique comprenant le médicament micronisé est également dévoilée.

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