Process for modifying drug crystal formation

Details Process for modifying drug crystal formation Process for modifying drug crystal formation

C - Chemistry, Metallurgy

07

D

C07D 307/88 (2006.01) A61K 9/14 (2006.01) A61K 9/28 (2006.01) A61K 31/365 (2006.01)

Patent

CA 2509796

A process for modifying the crystal habit of acicular drug substances, crystals obtained by such a process, and particular crystal forms or modifications of mycophenolic acid or mycophenolate sodium are provided, as well as pharmaceutical compositions comprising the crystals, methods of treatment and uses thereof.

La présente invention se rapporte à un procédé qui permet de modifier le faciès cristallin de substances médicamenteuses aciculaires, aux cristaux obtenus selon ce procédé, et à des formes ou modifications particulières des cristaux de l'acide mycophénolique ou du mycophénolate de sodium, de même qu'à des compositions pharmaceutiques renfermant lesdits cristaux, à des procédés de traitement dans lesquels lesdites compositions sont utilisées et à des procédés d'utilisation de ces dernières.

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