Process for obtaining a concentrate of von willebrand factor...

Details Process for obtaining a concentrate of von willebrand factor... Process for obtaining a concentrate of von willebrand factor...

C - Chemistry, Metallurgy

07

K

C07K 14/745 (2006.01) A61K 38/36 (2006.01) A61K 38/37 (2006.01) A61P 7/04 (2006.01) C07K 1/34 (2006.01) C07K 14/755 (2006.01)

Patent

CA 2645701

Process for the preparation of a concentrate of Von Willebrand Factor or a complex of Factor VIII/Von Willebrand Factor and use of the same. The process is characterised by the preparation of a solution of Von Willebrand Factor or a complex of Factor VIII/Von Willebrand Factor which contains VWF and a concentration of up to 12 IU VWF:RCo/ml and a Von Willebrand Factor/Factor VIII ratio of 0.4 or more; and then proceeding with nanofiltration of the solution prepared in a) through a filter having a pore size of less than 35 nanometres.

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