C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 21/02 (2006.01)
Patent
CA 2582726
The present invention relates to the manufacture of recombinant antibodies of therapeutic quality. In particular, the invention relates to methods for increasig the yield of cuntional antibody from large scale fermentations whereby a cultured host cell sample is subjected to a freeze-thaw treatment step.
Cette invention concerne la fabrication d'anticorps de recombinaison de qualité thérapeutique. Cette invention concerne plus particulièrement des procédés permettant d'augmenter la production d'anticorps fonctionnels à partir de fermentations sur grande échelle, dans lesquelles un échantillon de cellules hôtes cultivées est soumis à une étape de traitement par congélation-décongélation.
Sehdev Mukesh
Spitali Mariangela
Robic
Ucb Pharma S.a.
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