Process for obtaining antibodies

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 21/02 (2006.01)

Patent

CA 2582726

The present invention relates to the manufacture of recombinant antibodies of therapeutic quality. In particular, the invention relates to methods for increasig the yield of cuntional antibody from large scale fermentations whereby a cultured host cell sample is subjected to a freeze-thaw treatment step.

Cette invention concerne la fabrication d'anticorps de recombinaison de qualité thérapeutique. Cette invention concerne plus particulièrement des procédés permettant d'augmenter la production d'anticorps fonctionnels à partir de fermentations sur grande échelle, dans lesquelles un échantillon de cellules hôtes cultivées est soumis à une étape de traitement par congélation-décongélation.

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