Process for obtaining l-dihydroorotic acid and use thereof

Details Process for obtaining l-dihydroorotic acid and use thereof Process for obtaining l-dihydroorotic acid and use thereof

G - Physics

01

N

G01N 30/02 (2006.01) B01D 15/36 (2006.01) B01J 41/20 (2006.01) G01N 30/32 (2006.01) G01N 30/64 (2006.01)

Patent

CA 2315326

The invention relates to a process for obtaining L-dihydroorotic acid by chromatography on an anionic exchange material in a base water mixture under a pressure from about 1.1 MPa to about 40 MPa. The process can be used to investigate the in vitro and in vivo activity of N-(4-trifluoromethylphenyl)-5- methylisoxazole-4-carboxamide, N-(4-trifluoromethylphenyl)-2-cyano-3- hydroxycrontonamide and similar compounds.

L'invention concerne un procédé d'obtention d'un acide L-dihydro-orotique par chromatographie sur un matériau échangeur d'anions, dans un mélange eau-base, à une pression comprise entre environ 1,1 MPa et environ 40 MPa. Ce procédé peut être utilisé pour étudier l'activité in vitro et in vivo de N-(4-trifluorométhylphényl)-5-méthylisoxazole-4-carboxamide, de N-(4-trifluorométhylphényl)-2-cyano-3-hydroxycrontonamide et de composés similaires.

Affiliated with

Also associated with

Rating

Process for obtaining l-dihydroorotic acid and use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for obtaining l-dihydroorotic acid and use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for obtaining l-dihydroorotic acid and use thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1864683