C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/64 (2006.01) C07K 7/56 (2006.01)
Patent
CA 2074759
120/AOR60 18481 TITLE OF THE INVENTION PROCESS FOR PHOSPHATE ESTER COMPOUNDS OF CERTAIN CYCLOHEXAPEPTIDES ABSTRACT OF THE DISCLOSURE A facile process for preparing a compound of the formula or a salt thereof, wherein R, R1, R2, R3, R4, X, X1 Y and Z are as defined in the specification, by direct phosphorylation of the corresponding phenolic compound with tetrabenzyl pyrophosphate in the presence of lithium hydroxide is described.
Balkovec James M.
Loewe Mallory F.
Mathre David J.
Balkovec James M.
Loewe Mallory F.
Mathre David J.
Merck & Co. Inc.
Swabey Ogilvy Renault
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