Process for preparation of 1-benzylimidazole compound, and...

Details Process for preparation of 1-benzylimidazole compound, and... Process for preparation of 1-benzylimidazole compound, and...

C - Chemistry, Metallurgy

07

D

402/270, 260/315

C07D 233/56 (2006.01) C07D 233/54 (2006.01) C07D 521/00 (2006.01) C08G 59/40 (2006.01)

Patent

CA 1337428

Disclosed is a process for the preparation of a 1-benzylimidazole compound represented by the following general formula: Image wherein R2 represents a lower alkyl group or phenyl group, and R4 represents a hydrogen atom or a methyl group, which comprises heating and to react a 1-unsubstituted imidazole compound represented by the following general formula: Image wherein R2 and R4 are as defined above, with benzyl alcohol in the presence of a carboxylic acid, a carboxylic anhydride, a benzyl ester thereof or a lower alkyl ester thereof, and neutralizing the reaction product with an alkali.

610304

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