Process for preparation of 3-piperazinylbenzisothiazoles

Details Process for preparation of 3-piperazinylbenzisothiazoles Process for preparation of 3-piperazinylbenzisothiazoles

C - Chemistry, Metallurgy

07

D

C07D 417/04 (2006.01) C07D 275/04 (2006.01) C07D 275/06 (2006.01)

Patent

CA 2217137

The present invention is directed to a process for preparing 3-piperazinylbenzisothiazoles. The process comprises reacting a specified 3-halo-1,2-benzisothiazole or 2-cyanobenzenesulfenyl halide in the presence of an alkylene glycol derivative. The process is industrially effective, easy and economical and can provide useful intermediates for the production of pharmaceutical preparations.

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