Process for preparation of a solid form for oral use based...

Details Process for preparation of a solid form for oral use based... Process for preparation of a solid form for oral use based...

A - Human Necessities

61

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167/229

A61K 31/44 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 9/52 (2006.01)

Patent

CA 1253079

ABSTRACT Process for preparation of a solid administration form for oral use based on nifedipine with controlled release of the active substance, characterized by the fact that a mixture of nifedipine crystals having a specific surface area between 0.1 and 0.4 m2/9 is prepared, said mixture of crystals is blended with an equal amount by weight of auxiliary vehicle substances, and the resulting mixture so obtained is applied on spheroids of inert substances, by means of suitable binders, in coating pans.

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