Process for preparation of .alpha.-alkoxy acetic acids and...

C - Chemistry – Metallurgy – 07 – C

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C07C 51/367 (2006.01) C07C 59/125 (2006.01) C07C 59/66 (2006.01) C07C 323/20 (2006.01) C07C 323/62 (2006.01)

Patent

CA 2019230

8645N ABSTRACT A process for producing an .alpha.-alkoxy acetic acids and salts thereof which comprises reacting an alcohol of the formula R-OH wherein R is alkyl, substituted alkyl, or cycloalkyl, or cycloalkyl alkyl with a base in an aprotic organic solvent to give an alkoxide followed by removal of the organic solvent and reaction of the alkoxide with a salt of a monohaloacetic acid in a polar aprotic solvent such as DMSO to give the corresponding alkoxyacetate salt which then may be recovered or may optionally be converted to the corresponding acid by contacting the alkoxy acetate salt with an acid.

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