C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
260/321, 260/472
C07C 57/30 (2006.01) C07C 43/307 (2006.01) C07C 43/315 (2006.01) C07C 45/46 (2006.01) C07C 45/63 (2006.01) C07C 49/80 (2006.01) C07C 51/00 (2006.01) C07C 59/64 (2006.01) C07C 69/612 (2006.01) C07D 209/44 (2006.01) C07D 209/46 (2006.01) C07D 303/48 (2006.01) C07D 317/20 (2006.01) C07D 317/24 (2006.01) C07D 333/22 (2006.01) C07D 333/24 (2006.01)
Patent
CA 1186318
ABSTRACT OF THE DISCLOSURE The invention is a process for preparing an alpha-aromatic group substituted alkanoic acid or its ester of the general formula Image (I) wherein Ar represents an aromatic group and R1 represents a hydrogen atom or a saturated aliphatic group, or Ar and R1 may form a condensed ring together with the carbom atom to which they are bonded; and R2 represents a hydrogen atom, an alkyl group, or a hydroxyalkyl group. In the process an alpha- sulfonyloxyketone acetal of the general formula Image (II) wherein R3 and R4, independently from each other, represent an alkyl group, or taken together, represent an alkylene group; R5 represents a substituted or unsubstituted alkyl group or an aromatic group; and Ar and R1 are as defined above, is hydrolyzed, or treated with an agent having affinity for oxygen.
385670
Kitajima Kouji
Mitamura Shuichi
Tsuchihashi Genichi
Smart & Biggar
Syntex Pharmaceuticals International Limited
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