Process for preparation of aspartylphenylalanine alkyl esters

C - Chemistry – Metallurgy – 12 – P

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195/128.7

C12P 21/02 (2006.01) C07K 5/072 (2006.01)

Patent

CA 1195272

- 28 - PROCESS FOR PREPARATION OF ASPARTYLPHENYLALANINE ALKYL ESTERS ABSTRACT OF THE DISCLOSURE .alpha.-L-aspartylphenylalanine lower alkyl esters are prepared by a process wherein L-aspartic acid and a lower alkyl ester of L-phenylalanine are contacted with a culture or treated culture product of a microorganism belonging to the genus Pseudomonas, Alcaligenes, Torulopsis, Rhodotorula or Sporobolomyces and being capable of producing a .alpha.-L- -aspartyl-L-phenylalanine lower alkyl ester from L-aspartic acid and a lower alkyl ester of L-phenylalanine.

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