Process for preparation of d-proline derivatives by means of...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/80 (2006.01) C12N 1/20 (2006.01) C12N 9/78 (2006.01) C12P 13/24 (2006.01)

Patent

CA 2257542

The invention relates to novel micro-organisms which are able to utilise, as the sole nitrogen source, a guanidine valerianic acid derivative of the general formula (V), in which R1 is hydrogen or hydroxy, and R2 is a halogen atom or -NH2. It also relates to a novel enzyme with amidinohydrolase activity, and a novel process for preparation of D-proline derivatives from a L-arginine derivative.

L'invention concerne de nouveaux micro-organismes capables d'utiliser, comme source unique d'azote, un dérivé de l'acide guanidine-valérianique, de formule générale (V), dans laquelle R?1¿ désigne un hydrogène ou un hydroxy et R?2¿ désigne un atome d'halogène ou -NH¿2?. L'invention concerne en outre une nouvelle enzyme à activité amidinohydrolase, ainsi qu'un nouveau procédé de fabrication de dérivés de D-proline à partir d'un dérivé de L-arginine.

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