C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/12 (2006.01) A61K 31/40 (2006.01) A61P 1/00 (2006.01)
Patent
CA 2329210
The invention relates to a new method for producing N-methyl-N- [(1S)- 1- phenyl-2- ((3S)-3- hydroxypyrrolidine- 1-yl)ethyl]- 2,2-diphenyl acetamide or N-methyl- N-[(1R)- 1-phenyl-2- ((3R)-3- hydroxypyrrolidine- 1- yl)ethyl]- 2,2-diphenyl acetamide and to the new compounds N-methyl- N-[(1S)- 1-phenyl- 2-((3S)- 3-hydroxypyrrolidine- 1- yl)- ethane] and N-methyl-N- [(1R)- 1-phenyl-2- ((3R)-3- hydroxypyrrolidine- 1- yl)- ethane] produced as intermediate products.
L'invention concerne un nouveau procédé permettant la production au choix de N-Méthyl-N-((1S)-1-phényl-2-((3S)-3-hydroxypyrrolidin-1-yl)éthyl)-2,2-diphénylacétamide ou de N-Méthyl-N-((1R)-1-phényl-2-((3R)-3-hydroxy-pyrrolidin-1-yl)éthyl)-2,2-diphénylacétamide ainsi que les nouveaux composés N-Méthyl-N-((1S)-1-phényl-2-((3S)-3-hydroxypyrrolidin-1-yl)-éthane) et N-Méthyl-N-((1R)-1-phényl-2-((3R)-3-hydroxypyrrolidin-1-yl)-éthane) qui sont produits comme produits intermédiaires.
Ackermann Karl-August
Bathe Andreas
Budak Jens
Gottschlich Rudolf
Helfert Bernd
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
Tioga Pharmaceuticals Inc.
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