Process for preparation of esculetin compounds, esculetin...

C - Chemistry – Metallurgy – 07 – D

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C07D 311/16 (2006.01) A01N 31/16 (2006.01) A01N 35/04 (2006.01) A01N 37/02 (2006.01) A01N 37/12 (2006.01) A01N 43/16 (2006.01) A01N 43/30 (2006.01) A01N 43/90 (2006.01) C07C 43/23 (2006.01) C07C 45/00 (2006.01) C07C 45/45 (2006.01) C07C 45/51 (2006.01) C07C 45/71 (2006.01) C07C 46/06 (2006.01) C07C 46/08 (2006.01) C07C 47/565 (2006.01) C07C 47/575 (2006.01) C07C 69/017 (2006.01) C07D 317/46 (2006.01) C07D 493/04 (2006.01)

Patent

CA 2433578

Provided are esculetin compounds, intermediates thereof, a process for preparation of the esculetin compounds, and antimould and herbicide compositions for agricultural and horticultural use, containing the compounds or the intermediates. The process for preparation of the esculetin compounds is an industrially practicable one which enables the preparation of esculetin compounds of the general formula (2) at a low cost in high yield and is characterized by cyclizing a trihydroxy- benzaldehyde of the general formula (1) with acetic anhydride or the like in an aprotic polar solvent in the presence of a weak base. (1) (2)

L'invention concerne des composés d'esculetine, des intermédiaires de ces derniers, un procédé de préparation des composés d'esculetine et des compositions antifongiques et herbicides contenant les composés ou les intermédiaires à des fins agricoles ou horticoles. Le procédé de préparation des composés d'esculetine est un procédé industriellement réalisable qui permet la préparation des composés d'esculetine de formule générale (2) à un faible coût à rendement élevé et qui se caractérise par la cyclisation d'un trihydroxy-benzaldéhyde de formule générale (I) avec de l'anhydride acétique ou similaire dans un solvant aprotique polaire en présence d'une base faible.

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