Process for preparation of integrin receptor antagonist...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 239/02 (2006.01) C07D 401/00 (2006.01) C07D 471/02 (2006.01) C07D 471/04 (2006.01) C07D 487/02 (2006.01)

Patent

CA 2424304

A novel process is provided for the preparation of chiral intermediates useful in the asymmetric syntheses of .alpha.v.beta.3 integrin receptor antagonists. Also provided are the enantiomerically enriched intermediates that are obtained from the process.

L'invention concerne un nouveau procédé de préparation d'intermédiaires chiraux utilisés dans la synthèse asymétrique des antagonistes du récepteur de l'intégrine .alpha.v.beta.3. Cette invention concerne également des intermédiaires énantiomériquement enrichis, obtenus selon ledit procédé.

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