Process for preparation of liquid dosage form containing...

A - Human Necessities – 61 – K

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A61K 9/08 (2006.01) A61K 31/192 (2006.01)

Patent

CA 2614089

A process for preparing a stable aqueous dosage form of sodium 4- phenylbutyrate, including such dosage forms in a highly concentrated solution, as well as methods for making 4-phenylbutyrate and 4-phenylbutyric acid, and for using 4-phenylbutyrate. The stable aqueous dosage forms do not freeze at 0~ C.

L'invention concerne un procédé permettant de préparer une forme posologique aqueuse stable de 4-phénylbutyrate de sodium, comprenant ces formes posologiques dans une solution hautement concentrée ainsi que des procédés permettant de fabriquer du 4-phénylbutyrate et de l'acide 4-phenylbutyrique et d'utiliser du 4-phénylbutyrate. Les formes posologiques aqueuses stables ne gèlent pas à 0° C.

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