Process for preparation of sulfonamide derivatives and...

Details Process for preparation of sulfonamide derivatives and... Process for preparation of sulfonamide derivatives and...

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/405 (2006.01) A61P 29/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2406401

A process for the preparation of compound (I'): which is characterized by reacting in a solvent a compound of the general formula (III): (wherein X is halogeno) with p-tolylacetylene, a cuprous salt, a catalyst, and a base, and then treating the resulting reaction mixture with an acid.

L'invention concerne un procédé permettant de préparer d'un composé (I'): (I'), consistant à faire réagir, dans un solvant, un composé représenté par la formule générale (III): (III), (dans laquelle X représente halogène) avec du p-toylacétylène, un sel cuivreux, un catalyseur, et une base; puis à traiter le mélange de réaction obtenu avec un acide.

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