Process for preparing 1,4-dihydropyridine compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 417/06 (2006.01) C07D 211/90 (2006.01) C07D 401/06 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01) C07D 453/02 (2006.01) C07F 9/59 (2006.01)

Patent

CA 2327944

A process for preparing a 1,4-dihydropyridine compound comprising contacting an enamine compound (see formula I) and a compound having a structure of (see formula II) in the presence of a base; and treating the reaction mixture thus obtained in the presence of an acid or a combination of acids under mild reaction conditions. A resulting 1,4-dihydropyridine compound is useful as an anti-inflammatory agent or the like.

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