Process for preparing (1-oxo-2-phenyl, halophenyl or...

Details Process for preparing (1-oxo-2-phenyl, halophenyl or... Process for preparing (1-oxo-2-phenyl, halophenyl or...

C - Chemistry, Metallurgy

07

D

260/329.4, 260/5

C07D 333/24 (2006.01) C07C 45/46 (2006.01) C07C 45/66 (2006.01) C07C 45/75 (2006.01) C07C 49/755 (2006.01) C07C 49/84 (2006.01) C07C 59/90 (2006.01) C07D 333/22 (2006.01)

Patent

CA 1039295

A B S R A C T The invention relates to processes for preparing [1-oxo-2-phenyl, halophenyl or thienyl-2-methyl-6,7-dichloro- 5-indanyloxy]acetic acid, which have diuretic, saluretic and uricosuric activity. The process involves the use of novel ubterneduates having the structures: Image where R2 is phenyl, halophenyl or theinyl and R is CH2COOH, R1 or CH2COOR1 where, R1 is lower alkyl or haloloweralkyl, aryl and nuclear substituted derivatives aralkyl having from 7 to 20 carbon atoms, and X is OH, halo, and acid ester moieties.

210648

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