C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/64 (2006.01)
Patent
CA 2619731
Disclosed is a commercially suitable method for producing a 1-substituted-5- acylimidazole compound. A 1-substituted-5-acylimidazole compound is produced with a high position selectivity by reacting an N-substituted amidine compound or a salt thereof with a ketone compound in the presence of a base.
La présente invention concerne un procédé approprié sur le plan commercial de production d~un composé 5-acylimidazole substitué en position 1. Un composé 5-acylimidazole substitué en position 1 est produit avec une sélectivité de position élevée en faisant réagir un composé amidine N-substitué ou un sel de celui-ci avec un composé cétone en présence d'une base.
Nishino Shigeyoshi
Oda Hiroyuki
Omata Yoji
Takigawa Shinya
Yokoyama Shuji
Smart & Biggar
Ube Industries Ltd.
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