C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 9/00 (2006.01) A61K 31/575 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2608539
Process for preparing 3.alpha.-7.alpha.(.beta.)-dihydroxy-6.alpha.(.beta.)- alkyl-5.beta.-cholanic acid (I) in which R is a linear or branched C1-C5 alkyl and the relative intermediates 3.alpha.-hydroxy-6.beta.-alkyl-7-keto-5.beta.- cholanic (VIII) and 3.alpha.-hydroxy-6.alpha.-alkyl-7-keto-5.beta.-cholanic (IX).
Procédé d'élaboration d'acide 3a-7a(ß)-dihydroxy-6a(ß)-alkyle-5ß-cholanique (I), R étant C1-C5 alkyle linéaire ou ramifié, et intermédiaires respectifs 3a-hydroxy-6ß- alkyle-7-kéto-5ß-cholanique (VIII) et 3a-hydroxy-6a-alkyle-7-kéto-5ß-cholanique (IX).
Ferrari Massimo
Pellicciari Roberto
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Erregierre S.p.a.
Intercept Pharmaceuticals Inc.
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